Antibacterial, Antioxidant Activity of Ethanolic Plant Extracts of Some Species and Their DART-ToF-MS Profiling.

Journal: Evidence-based complementary and alternative medicine : eCAM
Published Date:

Abstract

Abdallah & Sa'ad and Desr. are commonly used in the Saudi Arabia folk medicine. They are potent in treating the ulcers and skin diseases. The lack of information about their biological activities led us to investigate the possible biological activities by determination of antibacterial and antioxidant activities of total ethanolic extracts and various fractions. Total flavonoid contents of the plants were determined by colorimetric method while total phenols were determined by using Folin-Ciocalteu method. antibacterial activity was studied against , , and , and the total antioxidant capacity was evaluated by radical scavenging method. IC were found to be 21.81, 17.62, and 3.31 g/mL for , , and vitamin C, respectively, while the lowest MIC value of 0.25 mg/mL was recorded with extract against Around 21 compounds are tentatively elucidated from both plants using rapid, simple, and high-resolution analytical technique for chemical profiling of natural compounds by direct analysis in real-time of flight-mass spectrometry, of which 17 were not isolated or reported previously.

Authors

  • Asma'a Al-Rifai
    Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
  • Ahmad Aqel
    Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
  • Tarfah Al-Warhi
    Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
  • Saikh M Wabaidur
    Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
  • Zeid A Al-Othman
    Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
  • A Yacine Badjah-Hadj-Ahmed
    Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.

Keywords

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