The role of Lp-PLA and biochemistry parameters as potential biomarkers of coronary artery disease in Asian South-Indians: a case-control study.

Journal: Cardiovascular diagnosis and therapy
Published Date: Dec 1, 2017

Abstract

BACKGROUND: Coronary artery disease (CAD) is the leading cause of death and disability worldwide. Lipoprotein associated phospholipase A (Lp-PLA) is an emerging biomarker for inflammation that has shown association with CAD. Its significance in the Asian Indian population is not clearly known. We sought to compare the possible association of various biomarkers of atherosclerosis along with Lp-PLA, in symptomatic individuals with CAD vs. healthy controls in Asian South-Indians.

Authors

  • Sai Giridhar Sairam
    Department of Chemistry, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, India.
  • Srikanth Sola
    Department of Cardiology, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, India.
  • Asha Barooah
    Department of Cardiology, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, India.
  • Sai Kiran Javvaji
    Department of Cardiology, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, India.
  • Jiten Jaipuria
    Department of Urology, Sri Sathya Sai Institute of Higher Medical Sciences, Prasanthi Gram, India.
  • Vijayalakshmi Venkateshan
    Department of Stem Cell Biology, National Institute of Nutrition, Hyderabad, India.
  • Janardhana Chelli
    Department of Chemistry, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, India.
  • Carani Balaraman Sanjeevi
    Department of Medicine, Karolinska Institutet, Solna, Sweden.

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