The correlations between serum amphiregulin and other clinicopathological factors in colorectal cancer.

Journal: Journal of gastrointestinal oncology
Published Date: Dec 1, 2017

Abstract

BACKGROUND: Amphiregulin (AREG) is one of the epidermal growth factor receptor (EGFR) ligands and plays the important roles in tumor progression and metastasis. Upregulation of AREG in colorectal cancer (CRC) tissues has been shown to correlate with depth of tumor invasion, nerve invasion and liver metastasis. We sought to investigate a correlation of serum AREG in CRC with clinicopathological parameters.

Authors

  • Chawalit Chayangsu
    Division of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Chualalongkorn University, Bangkok, Thailand.
  • Siriporn Khunsri
    Division of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Chualalongkorn University, Bangkok, Thailand.
  • Virote Sriuranpong
    Division of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Chualalongkorn University, Bangkok, Thailand.
  • Suebpong Tanasanvimon
    Division of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Chualalongkorn University, Bangkok, Thailand.

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