extract inhibits hepatocellular carcinoma via induction of caspase-dependent apoptosis.

Journal: OncoTargets and therapy
Published Date:

Abstract

INTRODUCTION: Cancer is a disease with a global burden and is a major and increasing threat to public health. The demand for new modalities to treat and prevent cancer is high. Given the toxic side effects of standard treatments, such as chemotherapy, there is greater research interest in naturally derived compounds due to their selective toxicity to cancer cells. This study aimed to test the anticancer activity of a crude extract of on hepatocellular carcinoma (HCC) HepG2 cell line.

Authors

  • Sinh Truong Nguyen
    Stem Cell Institute.
  • Khanh Linh Huynh
    Stem Cell Institute.
  • Huyen Lam-Thi Nguyen
    Stem Cell Institute.
  • Mai Nguyen Thi Thanh
    Faculty of Chemistry, University of Science, Vietnam National University Ho Chi Minh City.
  • Nhan Nguyen Trung
    Faculty of Chemistry, University of Science, Vietnam National University Ho Chi Minh City.
  • Hai Nguyen Xuan
    Faculty of Chemistry, University of Science, Vietnam National University Ho Chi Minh City.
  • Kim Phan Ngoc
    Stem Cell Institute.
  • Kiet Truong Dinh
    Medical Genetic Institute, Ho Chi Minh City, Vietnam.
  • Phuc Van Pham
    Stem Cell Institute.

Keywords

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