Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9.

Journal: Therapeutics and clinical risk management
Published Date: Dec 11, 2017

Abstract

BACKGROUND: A beneficial effect on cardiovascular risk may be obtained by improving lipid-related serum lipoprotein functions such as high-density lipoproteins (HDLs) cholesterol efflux capacity (CEC) and serum cholesterol loading capacity (CLC) and by reducing proprotein convertase subtilisin kexin type 9 (PCSK9), independently of lipoprotein concentrations.

Authors

  • Maria Pia Adorni
    Department of Food and Drug, University of Parma, Parma.
  • Nicola Ferri
    Dipartimento di Scienze del Farmaco, Università degli Studi di Padova, Padua, Italy.
  • Silvia Marchianò
    Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan.
  • Valentina Trimarco
    Department of Neurosciences.
  • Francesco Rozza
    Hypertension Research Center, Federico II University, Naples, Italy.
  • Raffaele Izzo
    Hypertension Research Center, Federico II University, Naples, Italy.
  • Franco Bernini
    Department of Food and Drug, University of Parma, Parma.
  • Francesca Zimetti
    Department of Food and Drug, University of Parma, Parma.

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