An exploration of distinguishing subjective cognitive decline and mild cognitive impairment based on resting-state prefrontal functional connectivity assessed by functional near-infrared spectroscopy.

Journal: Frontiers in aging neuroscience
Published Date: Jan 8, 2025

Abstract

PURPOSE: Functional near-infrared spectroscopy (fNIRS) has shown feasibility in evaluating cognitive function and brain functional connectivity (FC). Therefore, this fNIRS study aimed to develop a screening method for subjective cognitive decline (SCD) and mild cognitive impairment (MCI) based on resting-state prefrontal FC and neuropsychological tests via machine learning.

Authors

  • Zhengping Pu
    Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Hongna Huang
    Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Man Li
    Department of Psychogeriatrics, Kangci Hospital of Jiaxing, Tongxiang, Zhejiang, China.
  • Hongyan Li
    Department of Psychogeriatrics, Kangci Hospital of Jiaxing, Tongxiang, Zhejiang, China.
  • Xiaoyan Shen
    Department of Psychogeriatrics, Kangci Hospital of Jiaxing, Tongxiang, Zhejiang, China.
  • Qingfeng Wu
    Department of Psychogeriatrics, Kangci Hospital of Jiaxing, Tongxiang, Zhejiang, China.
  • Qin Ni
    Department of Psychogeriatrics, Kangci Hospital of Jiaxing, Tongxiang, Zhejiang, China.
  • Yong Lin
    Department of Psychogeriatrics, Kangci Hospital of Jiaxing, Tongxiang, Zhejiang, China.
  • Donghong Cui
    Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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