Impact of vitamin D status on statin-induced myopathy.

Journal: Journal of clinical & translational endocrinology
Published Date: Nov 23, 2016

Abstract

INTRODUCTION: There is a multitude of evidence supporting the benefit of statin use in cardiovascular disease; however, statin-induced myopathy is a major reason for statin discontinuation and non-adherence. Vitamin D deficiency has been independently associated with muscle weakness and severe myopathy, and may be a confounder for statin-induced myopathies. Since there is no consensus on a treatment course of action for statin-induced myopathy, investigation into potential confounders to elucidate the dynamics of statin-induced myopathy is warranted.

Authors

  • Krista D Riche
    The University of Mississippi, School of Pharmacy, Jackson, MS, United States.
  • Justin Arnall
    Wake Forest University, Winston-Salem, NC, United States.
  • Kristin Rieser
    The University of Mississippi, School of Pharmacy, Jackson, MS, United States.
  • Honey E East
    Premier Medical Group, Jackson, MS, United States.
  • Daniel M Riche
    The University of Mississippi, School of Pharmacy, Jackson, MS, United States.

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