Donor hepatitis C status is not associated with an increased risk of acute rejection in kidney transplantation.

Journal: Surgery in practice and science
Published Date: Feb 6, 2024

Abstract

INTRODUCTION: In renal transplantation, donor hepatitis C virus (HCV) status is crucial to consider when selecting a recipient given the high likelihood of transmission. We analyzed the effect of donor HCV status on post-renal transplant rejection and virologic infectious outcomes using electronic health record data from multiple US health care organizations.

Authors

  • John C Johnson
    Department of Surgery, Division of Multiorgan Transplant and Hepatobiliary Surgery, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0655, USA.
  • Trine Engebretsen
    Department of Surgery, Division of Multiorgan Transplant and Hepatobiliary Surgery, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0655, USA.
  • Muhammad Mujtaba
    Department of Medicine, Division of Transplant Nephrology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0655, USA.
  • Heather L Stevenson
    Department of Pathology, Division of Transplant Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0655, USA.
  • Rupak Kulkarni
    Department of Surgery, Division of Multiorgan Transplant and Hepatobiliary Surgery, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0655, USA.
  • A Scott Lea
    Department of Medicine, Division of Transplant Infectious Disease, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0655, USA.
  • Akshata Moghe
    Department of Medicine, Division of Transplant Hepatology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0655, USA.
  • Ann Kathleen Gamilla-Crudo
    Department of Medicine, Division of Transplant Nephrology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0655, USA.
  • Syed Hussain
    Department of Medicine, Division of Transplant Nephrology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0655, USA.
  • Michael Kueht
    Department of Surgery, Division of Multiorgan Transplant and Hepatobiliary Surgery, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0655, USA.

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