Limited short-term effect of palliative radiation therapy on quantitative computed tomography-derived bone mineral density in femora with metastases.

Journal: Advances in radiation oncology
Published Date: Nov 10, 2016

Abstract

PURPOSE: The aim of this study was to determine the effect of single fraction (SF) and multiple fraction (MF) radiation therapy (RT) on bone mineral density (BMD) in patients with cancer and bone metastases in the proximal femur. We studied this effect in the radiation field and within metastatic lesions, and differentiated between lytic, blastic, and mixed lesions.

Authors

  • Florieke Eggermont
    Orthopaedic Research Laboratory, Radboud Institute for Health Sciences, Radboud university medical center, Nijmegen, The Netherlands.
  • Loes C Derikx
    Orthopaedic Research Laboratory, Radboud Institute for Health Sciences, Radboud university medical center, Nijmegen, The Netherlands.
  • Nico Verdonschot
    Orthopaedic Research Laboratory, Radboud Institute for Health Sciences, Radboud university medical center, Nijmegen, The Netherlands.
  • Gerjon Hannink
    Orthopaedic Research Laboratory, Radboud Institute for Health Sciences, Radboud university medical center, Nijmegen, The Netherlands.
  • Robert S J P Kaatee
    Radiotherapeutic Institute Friesland, Leeuwarden, The Netherlands.
  • Esther Tanck
    Orthopaedic Research Laboratory, Radboud Institute for Health Sciences, Radboud university medical center, Nijmegen, The Netherlands.
  • Yvette M van der Linden
    Department of Radiotherapy, Leiden University Medical Center, Leiden, The Netherlands.

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