A Pilot Longitudinal Study on Cerebrospinal Fluid (CSF) Tau Protein in Alzheimer's Disease and Vascular Dementia.

Journal: Shanghai archives of psychiatry
Published Date: Oct 25, 2016

Abstract

BACKGROUND: Alzheimer's disease (AD) has high a prevalence rate, high medical costs, and care difficulties, and has become a serious social and economic problem in our aging society. So far, there has not been a reliable and objective diagnostic criteria for AD found. In recent years, there have been many domestic and foreign studies on the biological markers of cerebrospinal fluid in the patients with AD, and high levels of the T-tau, P-tau found in cerebrospinal fluid (CSF) is at this point an indisputable fact. However, the relationship between these markers and the severity of dementia, as well as the development of the disease, should be further studied.

Authors

  • Haihong Wang
    Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.
  • Tao Wang
    Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Shixing Qian
    Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.
  • Li Ba
    Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.
  • Zhiguang Lin
    Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.
  • Shifu Xiao
    Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.

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