Properdin Levels in Individuals with Chemotherapy-Induced Neutropenia.

Journal: Open forum infectious diseases
Published Date: Dec 7, 2016

Abstract

BACKGROUND: Neutrophils produce and carry key components of the alternative pathway (AP) of complement, including properdin (P). The effect of chemotherapy-induced absolute neutropenia on circulating P levels and AP function has not been previously established.

Authors

  • Artsiom Tsyrkunou
    Departments of Medicine University of Massachusetts Medical School, Worcester.
  • Sarika Agarwal
    Departments of Medicine University of Massachusetts Medical School, Worcester.
  • Bibek Koirala
    Departments of Medicine University of Massachusetts Medical School, Worcester.
  • Robert W Finberg
    Departments of Medicine University of Massachusetts Medical School, Worcester.
  • Rajneesh Nath
    Departments of Medicine University of Massachusetts Medical School, Worcester.
  • Bruce Barton
    Departments of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester.
  • Stuart M Levitz
    Departments of Medicine University of Massachusetts Medical School, Worcester.
  • Jennifer P Wang
    Departments of Medicine University of Massachusetts Medical School, Worcester.
  • Sanjay Ram
    Departments of Medicine University of Massachusetts Medical School, Worcester.

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