Simultaneous determination of nine bioactive compounds in Yijin-tang via high-performance liquid chromatography and liquid chromatography-electrospray ionization-mass spectrometry.

Journal: Integrative medicine research
Published Date: Apr 13, 2016

Abstract

BACKGROUND: Yijin-tang (YJ) has been used traditionally for the treatment of cardiovascular conditions, nausea, vomiting, gastroduodenal ulcers, and chronic gastritis. In this study, a simple and sensitive high-performance liquid chromatography (HPLC) method was developed for the quantitation of nine bioactive compounds in YJ: homogentisic acid, liquiritin, naringin, hesperidin, neohesperidin, liquiritigenin, glycyrrhizin, 6-gingerol, and pachymic acid.

Authors

  • Hye Jin Yang
    KM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.
  • Nam-Hui Yim
    KM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.
  • Kwang Jin Lee
    KM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.
  • Min Jung Gu
    KM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.
  • Bohyoung Lee
    KM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.
  • Youn-Hwan Hwang
    Herbal Medicine Research Division, Korea Institution of Oriental Medicine, Daejeon 34054, Republic of Korea.
  • Jin Yeul Ma
    KM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.

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