Compounding and stability evaluation of atorvastatin extemporaneous oral suspension using tablets or pure powder.

Journal: European journal of hospital pharmacy : science and practice
Published Date: Jun 15, 2016

Abstract

BACKGROUND: Statins are the first-line therapy for lowering high lipid levels. Atorvastatin calcium (AtC) is the most commonly prescribed statin. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase which converts HMG-CoA into mevalonic acid, a cholesterol precursor.

Authors

  • Abdel Naser Zaid
    Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus 00970, Palestine. anzaid@najah.edu.
  • Mohyeddin Assali
    Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University P.O. Box 7 Nablus Palestine m.d.assali@najah.edu.
  • Samah Zalmout
    Department of Pharmacy, An Najah National University, Nablus, Palestine.
  • Aseel Basheer
    Department of Pharmacy, An Najah National University, Nablus, Palestine.

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