Influence of Oral Progesterone Administration on Drug-Induced QT Interval Lengthening: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.

Journal: JACC. Clinical electrophysiology
Published Date: Dec 1, 2016

Abstract

OBJECTIVES: We tested the hypothesis that oral progesterone administration attenuates drug-induced QT interval lengthening.

Authors

  • James E Tisdale
    Department of Pharmacy Practice, College of Pharmacy, Purdue University, Indianapolis, Indiana.
  • Heather A Jaynes
    Department of Pharmacy Practice, College of Pharmacy, Purdue University, Indianapolis, Indiana.
  • Brian R Overholser
    Department of Pharmacy Practice, College of Pharmacy, Purdue University, Indianapolis, Indiana.
  • Kevin M Sowinski
    Department of Pharmacy Practice, College of Pharmacy, Purdue University, Indianapolis, Indiana.
  • David A Flockhart
    Division of Clinical Pharmacology, Department of Medicine, School of Medicine, Indiana University, Indianapolis, Indiana.
  • Richard J Kovacs
    Krannert Institute of Cardiology, Department of Medicine, School of Medicine, Indiana University, Indianapolis, Indiana.

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