Vitamin D Deficiency in Obsessive-Compulsive Disorder Patients with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections: A Case Control Study.

Journal: Noro psikiyatri arsivi
Published Date: Mar 1, 2016

Abstract

INTRODUCTION: Previous studies have indicated that vitamin D deficiency is common in psychiatric patients, particularly in those with neuropsychiatric disorders such as autism and schizophrenia. Vitamin D is an important neurosteroid hormone and immunomodulatory agent that also has bone metabolic effects. There has been an increasing interest in immune-related neuropsychiatric symptoms that are triggered by group A beta-hemolytic streptococcal infections. In this study, we aimed to compare the serum levels of vitamin D between obsessive-compulsive disorder (OCD) patients with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) and control subjects.

Authors

  • Gonca Çelik
    Department of Child and Adolescent Psychiatry, Çukurova University, School of Medicine, Adana, Turkey.
  • Didem Taş
    Department of Rheumatology Immunology, Çukurova University School of Medicine, Adana, Turkey.
  • Ayşegül Tahiroğlu
    Department of Child and Adolescent Psychiatry, Çukurova University, School of Medicine, Adana, Turkey.
  • Ayşe Avci
    Department of Child and Adolescent Psychiatry, Çukurova University, School of Medicine, Adana, Turkey.
  • Bilgin Yüksel
    Department of Pediatric Endocrinology, Çukurova University School of Medicine, Adana, Turkey.
  • Perihan Çam
    Department of Rheumatology Immunology, Çukurova University School of Medicine, Adana, Turkey.

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