Ready-to-use parenteral amiodarone: a feasibility study towards a long-term stable product formulation.

Journal: European journal of hospital pharmacy : science and practice
Published Date:

Abstract

OBJECTIVES: To determine the feasibility of preparing a long-term stable ready-to-use parenteral amiodarone formulation using cyclodextrins as dissolution enhancer.

Authors

  • Maartje S Jacobs
    Department of Clinical Pharmacy, Martini Hospital, Groningen, The Netherlands.
  • Marianne Luinstra
    Department of Clinical Pharmacy, Martini Hospital, Groningen, The Netherlands.
  • Jan Reindert Moes
    Department of Clinical Pharmacy, Martini Hospital, Groningen, The Netherlands.
  • Tiffany C Y Chan
    Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen, The Netherlands.
  • Isidor Minovic
    Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen, The Netherlands.
  • Henderik W Frijlink
    Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen, The Netherlands.
  • Herman J Woerdenbag
    Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen, The Netherlands.

Keywords

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