Jakyakgamcho-tang and Its Major Component, Paeonia Lactiflora, Exhibit Potent Anti-glycation Properties.

Journal: Journal of exercise nutrition & biochemistry
Published Date:

Abstract

PURPOSE: Advanced glycation end products (AGEs) have been implicated in the pathogenesis of diabetes and other age-related diseases. AGE inhibitors or breakers, such as aminoguanidine and alagebrium, have been proposed as therapeutic agents for AGE-related disorders. Jakyakgamcho-tang (JGT) is a well-known traditional herbal formula, which consists of the radix of Paeonia lactiflora Pallas (PR) and the radix and rhizome of Glycyrrhiza uralensis Fisch (GR). The purpose of this study was to evaluate the inhibitory and breaking activities of JGT, PR, and GR against AGEs.

Authors

  • Junghyun Kim
    Korean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon Republic of Korea.
  • Chan-Sik Kim
    Korean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon Republic of Korea.
  • Young Sook Kim
    Korean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon Republic of Korea.
  • Ik Soo Lee
    Korean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon Republic of Korea.
  • Jin Sook Kim
    Korean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon Republic of Korea.

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