Effects of antibiotic therapy on the early development of gut microbiota and butyrate-producers in early infants.

Journal: Frontiers in microbiology
Published Date: Jan 7, 2025

Abstract

BACKGROUND: Antibiotics, as the most commonly prescribed class of drugs in neonatal intensive care units, have an important impact on the developing neonatal gut microbiota. Therefore, comprehending the effects of commonly used antibiotic therapy on the gut microbiota and butyrate-producers in early infants could provide information for therapeutic decision-making in the NICU.

Authors

  • Jun Qiu
    The School of Pediatrics, Hengyang Medical School, University of South China, Hunan Children's Hospital, Hengyang, Hunan, China.
  • Sha Wu
    The School of Pediatrics, Hengyang Medical School, University of South China, Hunan Children's Hospital, Hengyang, Hunan, China.
  • Ruiwen Huang
    Department of Neonatology, Hunan Children's Hospital, Changsha, Hunan, China.
  • Zhenyu Liao
    Department of Neonatology, Hunan Children's Hospital, Changsha, Hunan, China.
  • Xiongfeng Pan
    Pediatrics Research Institute of Hunan Province, Hunan Children's Hospital, Changsha, Hunan, China.
  • Kunyan Zhao
    Pediatrics Research Institute of Hunan Province, Hunan Children's Hospital, Changsha, Hunan, China.
  • Yunlong Peng
    Pediatrics Research Institute of Hunan Province, Hunan Children's Hospital, Changsha, Hunan, China.
  • Shiting Xiang
    Pediatrics Research Institute of Hunan Province, Hunan Children's Hospital, Changsha, Hunan, China.
  • Yunhui Cao
    The School of Pediatrics, Hengyang Medical School, University of South China, Hunan Children's Hospital, Hengyang, Hunan, China.
  • Ye Ma
    Department of Neonatology, Hunan Children's Hospital, Changsha, Hunan, China.
  • Zhenghui Xiao
    The School of Pediatrics, Hengyang Medical School, University of South China, Hunan Children's Hospital, Hengyang, Hunan, China.

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