Retrospective analysis of amantadine response and predictive factors in intensive care unit patients with non-traumatic disorders of consciousness.

Journal: Frontiers in neurology
Published Date: Jan 6, 2025

Abstract

BACKGROUND: Disorders of consciousness (DoC) in non-traumatic ICU-patients are often treated with amantadine, although evidence supporting its efficacy is limited.

Authors

  • Corinna Blum
    Department of Neurology & Stroke, University Hospital Tübingen, Tübingen, Germany.
  • Constanze Single
    Department of Neurology & Stroke, University Hospital Tübingen, Tübingen, Germany.
  • Kornelia Laichinger
    Department of Neurology & Stroke, University Hospital Tübingen, Tübingen, Germany.
  • Anna Hofmann
    Department of Neurology/Neurodegenerative Diseases, University Hospital Tübingen, Tübingen, Germany.
  • Tim W Rattay
    Department of Neurology & Stroke, University Hospital Tübingen, Tübingen, Germany.
  • Kamaldeen Adeyemi
    Department of Neurology & Stroke, University Hospital Tübingen, Tübingen, Germany.
  • Reimer Riessen
    Department for Internal Medicine, University Hospital Tübingen, Tübingen, Germany.
  • Michael Haap
    Department for Internal Medicine, University Hospital Tübingen, Tübingen, Germany.
  • Helene Häberle
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Tübingen, Tübingen, Germany.
  • Ulf Ziemann
    Department of Neurology & Stroke, University Hospital Tübingen, Tübingen, Germany.
  • Annerose Mengel
    Department of Neurology & Stroke, Eberhard-Karls University of Tuebingen, Tuebingen, Germany.
  • Katharina Feil
    Department of Neurology & Stroke, University Hospital Tübingen, Tübingen, Germany.

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