Harnessing artificial intelligence in sepsis care: advances in early detection, personalized treatment, and real-time monitoring.

Journal: Frontiers in medicine
Published Date:

Abstract

Sepsis remains a leading cause of morbidity and mortality worldwide due to its rapid progression and heterogeneous nature. This review explores the potential of Artificial Intelligence (AI) to transform sepsis management, from early detection to personalized treatment and real-time monitoring. AI, particularly through machine learning (ML) techniques such as random forest models and deep learning algorithms, has shown promise in analyzing electronic health record (EHR) data to identify patterns that enable early sepsis detection. For instance, random forest models have demonstrated high accuracy in predicting sepsis onset in intensive care unit (ICU) patients, while deep learning approaches have been applied to recognize complications such as sepsis-associated acute respiratory distress syndrome (ARDS). Personalized treatment plans developed through AI algorithms predict patient-specific responses to therapies, optimizing therapeutic efficacy and minimizing adverse effects. AI-driven continuous monitoring systems, including wearable devices, provide real-time predictions of sepsis-related complications, enabling timely interventions. Beyond these advancements, AI enhances diagnostic accuracy, predicts long-term outcomes, and supports dynamic risk assessment in clinical settings. However, ethical challenges, including data privacy concerns and algorithmic biases, must be addressed to ensure fair and effective implementation. The significance of this review lies in addressing the current limitations in sepsis management and highlighting how AI can overcome these hurdles. By leveraging AI, healthcare providers can significantly enhance diagnostic accuracy, optimize treatment protocols, and improve overall patient outcomes. Future research should focus on refining AI algorithms with diverse datasets, integrating emerging technologies, and fostering interdisciplinary collaboration to address these challenges and realize AI's transformative potential in sepsis care.

Authors

  • Fang Li
    Department of General Surgery, Chongqing General Hospital, Chongqing, China.
  • Shengguo Wang
    Department of Stomatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Zhi Gao
    Department of Stomatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Maofeng Qing
    Department of Stomatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Shan Pan
    Department of Stomatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Yingying Liu
    Department of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
  • Chengchen Hu
    Department of Stomatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Keywords

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