Methotrexate-associated primary hepatic malignant lymphoma following hepatectomy: A case report.

Journal: International journal of surgery case reports
Published Date: Dec 21, 2016

Abstract

INTRODUCTION: Recently, immunosuppressant-associated malignant lymphoma (ML) cases have been increasing along with the development of several effective immunosuppressant drugs for rheumatoid arthritis (RA). Among methotrexate (MTX)-associated lymphoproliferative disorders, primary hepatic lymphoma (PHL) in patients with RA following surgical resection has not been reported previously.

Authors

  • Daisuke Takei
    Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima, Japan.
  • Tomoyuki Abe
    Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima, Japan. Electronic address: t.abe.hiroshima@gmail.com.
  • Hironobu Amano
    Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima, Japan; Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Japan.
  • Naomichi Hirano
    Department of Gastroenterology,Onomichi General Hospital, Onomichi, Hiroshima, Japan.
  • Tsuyoshi Kobayashi
    Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Japan.
  • Hideki Ohdan
    Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Japan.
  • Toshinori Kondo
    Kawasaki Medical School Hospital, Kurashiki, Okayama, Japan.
  • Masahiro Nakahara
    Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima, Japan.
  • Toshio Noriyuki
    Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima, Japan; Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Japan.

Keywords

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