Nanoparticle-mediated arresten gene inhibits neointimal formation of vein grafts: an experimental research.

Journal: Journal of thoracic disease
Published Date: Nov 1, 2016

Abstract

BACKGROUND: Recently, we established a new rat model of venous arterialization by grafting the jugular vein into carotid arteries. In many respects, the morphological features of this murine vascular graft model resemble those of human venous bypass graft diseases. Using this model, we studied nanoparticles that mediated the arresten gene to inhibit the neointimal formation of vein grafts.

Authors

  • Rong-Fei Wang
    Department of Vascular Surgery, Affiliated Jinan Central Hospital of Shandong University, Jinan 250013, China.
  • Qing-Yi Meng
    Department of Vascular Surgery, Affiliated Jinan Central Hospital of Shandong University, Jinan 250013, China.

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