AI Medical Compendium Journal:
Annals of translational medicine

Showing 1 to 10 of 13 articles

Gene-gene interaction: the curse of dimensionality.

Annals of translational medicine
Identified genetic variants from genome wide association studies frequently show only modest effects on the disease risk, leading to the "missing heritability" problem. An avenue, to account for a part of this "missingness" is to evaluate gene-gene i...

Risk factors of perfusion and diffusion abnormalities on MRI in hemispheric TIA: a case-control study.

Annals of translational medicine
BACKGROUND: To assess the prevalence and potential predictors of MR diffusion and perfusion abnormalities in a Chinese population with hemispheric transient ischemic attacks (TIA).

The analysis of pharmacokinetic and pharmacogenomic impact on gefitinib efficacy in advanced non-small cell lung cancer patients: results from a prospective cohort study.

Annals of translational medicine
BACKGROUND: The current study is aimed to examine the impact of pharmacokinetics and gene polymorphisms of enzymes involving in absorption, distribution, metabolism and excretion (ADME) on the efficacy of gefitinib in non-small cell lung cancer (NSCL...

Simple continuous suture to strengthen the closure of intra-muscle used in the removal of uni-portal video-assisted thoracoscopic surgery thoracic drainage tube.

Annals of translational medicine
BACKGROUND: Uni-portal video-assisted thoracoscopic surgery (VATS) has become a popular type of thoracic surgery. However, improvements to the closure of the single drainage tube hole are still in need.

Glasses-free 3D versus 2D video-assisted thoracoscopic thymectomy: a single-center short-term comparative study.

Annals of translational medicine
BACKGROUND: Thymectomy is widely used to for the treatment of thymomas, thymic cysts, thymic adenocarcinomas, and other thymic diseases. The development of video-assisted thoracoscopic surgery (VATS) thymectomy by our team offers the advantages of a ...

PEEP guided by electrical impedance tomography during one-lung ventilation in elderly patients undergoing thoracoscopic surgery.

Annals of translational medicine
BACKGROUND: To examine the influence of positive end-expiratory pressure (PEEP) settings on lung mechanics and oxygenation in elderly patients undergoing thoracoscopic surgery.

Respiratory parameters and acute kidney injury in acute respiratory distress syndrome: a causal inference study.

Annals of translational medicine
BACKGROUND: Assess the respiratory-related parameters associated with subsequent severe acute kidney injury in mechanically ventilated patients with acute respiratory distress syndrome (ARDS).

A fitting machine learning prediction model for short-term mortality following percutaneous catheterization intervention: a nationwide population-based study.

Annals of translational medicine
BACKGROUND: A suitable multivariate predictor for predicting mortality following percutaneous coronary intervention (PCI) remains undetermined. We used a nationwide database to construct mortality prediction models to find the appropriate model.

Restoration of FKBP51 protein promotes the progression of castration resistant prostate cancer.

Annals of translational medicine
BACKGROUND: As deregulation of androgen receptor (AR) signaling target genes is associated with tumorigenesis and the development of prostate cancer (PCa), AR signaling is the primary therapeutic target for PCa. Although patients initially responses ...

Maternal serum pentraxin 3 level in early pregnancy for prediction of gestational diabetes mellitus.

Annals of translational medicine
BACKGROUND: Our study aimed to reveal the relationship of maternal pentraxin 3 (PTX3)'s serum concentrations in early pregnancy with gestational diabetes mellitus (GDM) and to explore its potential in the prediction of GDM.