AI Medical Compendium Journal:
BioImpacts : BI

Showing 1 to 8 of 8 articles

Evaluating the presence of deregulated tumoral onco-microRNAs in serum-derived exosomes of gastric cancer patients as noninvasive diagnostic biomarkers.

BioImpacts : BI
Exosomal microRNAs (miRNAs) are emerging diagnostic biomarkers for different types of cancers. We aim to detect gastric cancer (GC)-specific miRNAs in serum exosomes with diagnostic potential. A pair of 43 tumor and tumor-adjacent tissue biopsies o...

Characterization of isolated compounds from spp. and their biological activity as anticancer molecules.

BioImpacts : BI
The genus is well known for its medicinal benefits from time immemorial. The present work reported the health-promoting properties of the biologically active molecules present in different species of the genus . Different solvent extracts of the t...

SU8/glass microchip capillary electrophoresis integrated with Pt electrodes for separation and simultaneous detection of phenylephrine and acetaminophen.

BioImpacts : BI
A new microfluidic-based method with electrochemical detection was developed for the simultaneous quantification of acetaminophen (AP) and phenylephrine (PHE) pharmaceuticals in the human blood and pharmaceuticals (e.g. tablet and drop). The separa...

Presence of pyrroloquinazoline alkaloid in attenuates inflammatory response through the downregulation of pro-inflammatory mediators in LPS stimulated RAW 264.7 macrophages.

BioImpacts : BI
Inflammation is the primary response caused due to harmful stimuli which are followed by the increased draining of plasma and immune cells from the body into the site of the injured tissue. A signaling cascade of growth factors and cytokines propaga...

Poly(ethylene glycol)-poly(ε-caprolactone)-based micelles for solubilization and tumor-targeted delivery of silibinin.

BioImpacts : BI
Silibinin is a naturally occurring compound with known positive impacts on prevention and treatment of many types of in general and cancer in particular. Silibinin is poorly water soluble which results in its insufficient bioavailability and lack o...

Spectrophotometric analysis of thrombolytic activity: SATA assay.

BioImpacts : BI
Measurement of thrombolytic activity is crucial for research and development of novel thrombolytics. It is a key factor in the assessment of the effectiveness of conventionally used thrombolytic therapies in the clinic. Previous methods used for the...

Chemiluminescence based immunoassay for the detection of heroin and its metabolites.

BioImpacts : BI
Continuous use of opiates causes drug-related illnesses, which poses an alarming situation to develop sensitive detection platform. In this study, a highly sensitive and reliable chemiluminescence immunoassay (CI) has been developed for the detectio...

Development and evaluation of exemestane-loaded lyotropic liquid crystalline gel formulations.

BioImpacts : BI
The use of liquid crystalline (LC) gel formulations for drug delivery has considerably improved the current delivery methods in terms of bioavailability and efficacy. The purpose of this study was to develop and evaluate LC gel formulations to deliv...