Computational and structural biotechnology journal
Mar 18, 2025
BACKGROUND: Accurate cardiotocography (CTG) interpretation is vital for the monitoring of fetal well-being during pregnancy and labor. Advanced artificial intelligence (AI) tools such as AI-large language models (AI-LLMs) may enhance the accuracy of ...
Computational and structural biotechnology journal
Oct 31, 2024
OBJECTIVE: This study investigated the ability of Large Language Models (LLMs) to provide accurate and consistent answers by focusing on their performance in complex gynecologic cancer cases.
Computational and structural biotechnology journal
Dec 29, 2023
() has become a particular concern due to the increasing incidence of antimicrobial resistance (AMR) observed worldwide. Using machine learning (ML) to predict AMR is a more efficient method than traditional laboratory testing. However, further imp...
Computational and structural biotechnology journal
Dec 20, 2023
The application of machine learning techniques in biological research, especially when dealing with limited data availability, poses significant challenges. In this study, we leveraged advancements in method development for predicting protein-protein...
Computational and structural biotechnology journal
Nov 17, 2023
Long non-coding ribonucleic acids (lncRNAs) have been shown to play an important role in plant gene regulation, involving both epigenetic and transcript regulation. LncRNAs are transcripts longer than 200 nucleotides that are not translated into func...
Computational and structural biotechnology journal
Jul 1, 2023
The primary aim of this research was to investigate potential differences of breast tumor morphologies across African American and Caucasian racial groups by utilizing machine learning (ML) and artificial intelligence (AI) methods. While breast cance...
Computational and structural biotechnology journal
Apr 29, 2023
Therapeutic protein, represented by antibodies, is of increasing interest in human medicine. However, clinical translation of therapeutic protein is still largely hindered by different aspects of developability, including affinity and selectivity, st...
Computational and structural biotechnology journal
Apr 28, 2023
A cross-ribosome binding site (cRBS) adjusts the dynamic range of transcription factor-based biosensors (TFBs) by controlling protein expression and folding. The rational design of a cRBS with desired TFB dynamic range remains an important issue in T...
Computational and structural biotechnology journal
Dec 26, 2018
Free radicals that form from reactive species of nitrogen and oxygen can react dangerously with cellular components and are involved with the pathogenesis of diabetes, cancer, Parkinson's, and heart disease. Cysteine amino acids, due to their reactiv...
Computational and structural biotechnology journal
Nov 1, 2016
This study describes the NMR-based method to determine the limit of quantitation (LOQ) and limit of detection (LOD) of cholesterol, a process-related impurity in the replication-deficient Herpes Simplex Virus (HSV) type 2 candidate vaccine HSV529. Th...