AI Medical Compendium Journal:
Computational toxicology (Amsterdam, Netherlands)

Showing 1 to 2 of 2 articles

Guided optimization of ToxPi model weights using a Semi-Automated approach.

Computational toxicology (Amsterdam, Netherlands)
The Toxicological Prioritization Index (ToxPi) is a visual analysis and decision support tool for dimension reduction and visualization of high throughput, multi-dimensional feature data. ToxPi was originally developed for assessing the relative toxi...

Performance of Machine Learning Algorithms for Qualitative and Quantitative Prediction Drug Blockade of hERG1 channel.

Computational toxicology (Amsterdam, Netherlands)
Drug-induced abnormal heart rhythm known as (TdP) is a potential lethal ventricular tachycardia found in many patients. Even newly released anti-arrhythmic drugs, like ivabradine with HCN channel as a primary target, block the hERG potassium current...