AIMC Journal:
Immunological investigations

BACKGROUND: Chronic inflammatory disorders represent a major global health burden characterized by persistent immune activation, oxidative stress, and progressive tissue dysfunction. Dysregulated redox signaling has positioned the Kelch-like ECH-asso...

BACKGROUND: Influenza A virus (IAV) infection induces complex antiviral immune responses, yet how innate sensing, host genetic susceptibility, and adaptive immune dysfunction converge remains incompletely understood. This study investigated periphera...

BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disease needing reliable biomarkers. This study aimed to identify potential RA biomarkers using WGCNA and machine learning, and analyze their correlation with disease activity and STAT3. M...

BACKGROUND: Sepsis is a major global health challenge characterized by a complex pathogenesis involving an early hyperinflammatory phase followed by a subsequent immunosuppressive state. Recent studies have revealed that dysregulation of fumarate met...

INTRODUCTION: Autoimmune thyroid diseases (AITDs), including Graves' disease and Hashimoto's thyroiditis, arise from genetic, epigenetic, and environmental disruption of immune tolerance. These conditions represent the extremes of thyroid autoimmunit...