The development of predictive understanding of bacterial resistance to antibiotics is one of the greatest challenges of modern medicine. Genome-scale metabolic models (GEMs) are mathematical representations of the metabolic network of a given organis...
Coxiella burnetii is a highly virulent intracellular pathogen and the causative agent of acute and chronic Q fever in humans. Central to its pathogenicity is the Dot/Icm type IV secretion system, which translocates more than 100 effector proteins int...
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