AIMC Journal:
Insect biochemistry and molecular biology

We identify PAN4 (GAYTFKIRRK), an AI-designed host-directed immunomodulatory peptide, as a modulator of intestinal immune homeostasis in Drosophila melanogaster. PAN4 lacks detectable bactericidal activity against Pseudomonas aeruginosa in vitro but ...

Monochamus saltuarius, a major vector of Bursaphelenchus xylophilus, relies on pheromone-mediated communication for successful reproduction, yet the metabolic and molecular basis of pheromone biosynthesis remains poorly understood. Here, we generated...