AI Medical Compendium Journal:
Iranian journal of pharmaceutical research : IJPR

Showing 51 to 60 of 62 articles

Physicochemical and Immunomodulatory Properties of Gum Exudates Obtained from and Some of Its Isolated Carbohydrate Biopolymers.

Iranian journal of pharmaceutical research : IJPR
Plants gums are complex mixtures of different polysaccharides with a variety of biological activities and pharmaceutical applications. Few studies have focused on physicochemical and biological properties of gums obtained from different plants. This ...

Preclinical Evaluation of Ga-MAA from Commercial Available Tc-MAA Kit.

Iranian journal of pharmaceutical research : IJPR
Tc-Macroaggregated Albumin (Tc-MAA) has been used as a perfusion agent. This study described development of the Ga-MAA via commercially available kits from Pars-Isotopes Company as a Tc-MAA kit. Ge/Ga generator was eluted with suprapure HCl (0.6 M, 6...

Single Layer Extended Release Two-in-One Guaifenesin Matrix Tablet: Formulation Method, Optimization, Release Kinetics Evaluation and Its Comparison with Mucinex Using Box-Behnken Design.

Iranian journal of pharmaceutical research : IJPR
Guaifenesin, a highly water-soluble active (50 mg/mL), classified as a BCS class I drug. Owing to its poor flowability and compressibility, formulating tablets especially high-dose one, may be a challenge. Direct compression may not be feasible. Bila...

Assessment of Magnetic Dextran-Spermine Nanoparticles for Capecitabine Delivery to Cancerous Cells.

Iranian journal of pharmaceutical research : IJPR
Cationic polymeric nanoparticles have great potential for developing drug delivery systems with limited side effects for tumor medication. The goal of this research is investigation of cationic dextran-spermine polymer (DS) efficacy for improvement o...

Preparation and Characterization of Three Tilmicosin-loaded Lipid Nanoparticles: Physicochemical Properties and Antibacterial Activities.

Iranian journal of pharmaceutical research : IJPR
Tilmicosin (TLM) is an important antibiotic in veterinary medicine with low bioavailability and safety. This study aimed to formulate and evaluate physicochemical properties, storage stability after lyophilization, and antibacterial activity of three...

Effectiveness of Vitamin D Supplement Therapy in Chronic Stable Schizophrenic Male Patients: A Randomized Controlled Trial.

Iranian journal of pharmaceutical research : IJPR
In this study, the aim was to determine whether adding vitamin D to the standard therapeutic regimen of schizophrenic male patients with inadequate vitamin D status could improve some aspects of the symptom burden or not. This study was an open paral...

Effects of Phenylglyoxal and N-ethylmaleimide Concentration on Mycophenolic Acid Production by ATCC16024.

Iranian journal of pharmaceutical research : IJPR
Mycophenolic acid is a secondary extracellular metabolite of strains with numerous pharmaceutical properties such as antibiotic and immunosuppressive uses. The aim of this work is the survey of the effect of phenylglyoxal and n-ethylmaleimide concen...

Preparation of Diaminedicarboxyplatinum (II) Functionalized Single-Wall Carbon Nanotube via Bingel Reaction as a Novel Cytotoxic Agent.

Iranian journal of pharmaceutical research : IJPR
Carbon nanotubes have unique properties like high stability, high surface to mass ratio and so on which make them suitable for medicinal purpose applications. Treatment of cancer by organoplatinum agents like Cisplatin has become unresponsive in most...

Mitochondrial Apoptosis Induced by Extract in Breast Cancer Cells.

Iranian journal of pharmaceutical research : IJPR
() commonly known as 'Roman chamomile' is a medicinal plant used for numerous diseases in traditional medicine, although its anticancer activity is unknown. The present study was carried out to investigate the anticancer as well as apoptotic activit...

Anti-inflammatory Effect of Amitriptyline on Ulcerative Colitis in Normal and Reserpine-Induced Depressed Rats.

Iranian journal of pharmaceutical research : IJPR
Depressive disorders are more common among persons with chronic diseases such as inflammatory bowel disease and anti-inflammatory effect of some antidepressants such as amitriptyline has been reported. Acetic acid colitis was induced in both reserpin...