Understanding the trajectory of Huntington's disease (HD) is critical for patient stratification and the development of targeted interventions. Traditionally, studies relied on age-CAG models to estimate disease onset and progression, based on the we...
BackgroundHuntington's disease (HD) is a hereditary neurodegenerative disorder, with pathological changes detectable by MRI before symptom onset. Quantitative MRI (qMRI) provides tissue-specific parameters and holds potential for capturing disease-re...
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