AI Medical Compendium Journal:
Journal of receptor and signal transduction research

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Design and molecular mechanism investigation of ALK inhibitors based on virtual screening and structural descriptor modeling.

Journal of receptor and signal transduction research
To address the challenges of target specificity and drug resistance in Anaplastic lymphoma kinase (ALK) inhibition, this study conducted a virtual screening of the BindingDB database, yielding 711 potential ALK inhibitors. Four QSAR models were estab...