AI Medical Compendium Journal:
Pathophysiology : the official journal of the International Society for Pathophysiology

Showing 1 to 4 of 4 articles

Circulating Levels of Endothelin-1 and Big Endothelin-1 in Patients with Essential Hypertension.

Pathophysiology : the official journal of the International Society for Pathophysiology
The role of endothelin-1 (ET-1) in the pathogenesis of hypertension (HTN) is not clearly established. There is evidence that its circulating levels are elevated in some forms of experimental and human HTN, but this was not a consistent finding. Based...

A Proteinase 3 Contribution to Juvenile Idiopathic Arthritis-Associated Cartilage Damage.

Pathophysiology : the official journal of the International Society for Pathophysiology
A full understanding of the molecular mechanisms implicated in the etiopathogenesis of juvenile idiopathic arthritis (JIA) is lacking. A critical role for leukocyte proteolytic activity (e.g., elastase and cathepsin G) has been proposed. While leukoc...

Extract Extenuates Venom-Induced Toxicities, Histopathological Impairments and Inflammation via Enhancement of Nrf2 Expression in Rats.

Pathophysiology : the official journal of the International Society for Pathophysiology
snakebite causes more fatalities than all other African snake species combined. reportedly possesses an antivenom property. Therefore, we evaluated the effectiveness of ethanol extract (MOE) against (EOV) toxicities. Thirty male rats were grouped...

Evaluation of Five International HBV Treatment Guidelines: Recommendation for Resource-Limited Developing Countries Based on the National Study in Nepal.

Pathophysiology : the official journal of the International Society for Pathophysiology
Hepatitis B virus (HBV) infects the liver, causing cirrhosis and cancer. In developed countries, five international guidelines have been used to make a decision for the management of patients with chronic HBV infection. In this review, since the guid...