Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Jul 20, 2018
The use of microbial cell culture a valuable tool for the biosynthesis of nanoparticles is considered a green technology as it is eco-friendly, inexpensive and simple. Here, the synthesis of nanosilver particle (AgNP) from the yeast, , gram (+), and...
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Dec 28, 2017
In the present study, we describe various pharmacological effects and computational analysis of nepetolide, a tricyclic clerodane-type diterpene, isolated from . Nepetolide concentration-dependently (1.0-1000 µg/mL) exhibited 1,1-diphenyl,2-picrylhyd...
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Dec 18, 2017
A rapid, simple and accurate micellar HPLC-method was adopted and validated for concurrent quantification of naltrexone hydrochloride (NTX) and bupropion hydrochloride (BUP). The proposed method was conducted on RP-18 LiChrosorb® column (150 mm × 4.6...
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Jul 11, 2017
Natural products of plant origin, which include essential oils (EO) could be used as a growth inhibitor of pathogenic and spoilage microflora in food. The objective of this study was to determine the antibacterial and antioxidant activity of 21 EO ag...
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Nov 12, 2016
Phytochemical investigation and chromatographic purification of the -hexane fraction of the aerial parts of the edible Saudi plant led to the isolation of β-sitosterol (), stigmasterol () and β-sitosterol-β-d-glucoside (). The cytotoxic effects of t...
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Nov 12, 2016
Nature is a source of many plant-based molecules used as pro- or drugs. species are native to Asia and the North Russia, and are traditionally used to treat various diseases. In turn, neither secondary metabolites of the species cultivated in the We...
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Sep 30, 2016
Various methods have been used to enhance production of chemically diverse phytochemicals especially medicinal natural products. With the advancement in nanotechnology, nanoparticles have been reported to have varying impact in plant growth and induc...
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Sep 30, 2016
Although albendazole is the drug-of-choice for the treatment of neurocysticercosis, its efficacy is limited due to its low bioavailability. An alternative for optimizing pharmacological treatment is through drug combinations. studies have shown tha...
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Jul 1, 2016
Tacrolimus is a potent immunosuppressant; however, it suffers from several problems such as poor water solubility (4-12 μg/mL), low and variable oral bioavailability in patients, and narrow therapeutic window that could not be solved by the currently...
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Mar 23, 2015
We studied the application of Taguchi orthogonal array (TOA) design during the development of an isocratic stability indicating HPLC method for glimepiride as per TOA design; twenty-seven experiments were conducted by varying six chromatographic fact...