AIMC Journal:
Smart molecules : open access

Drug-induced liver injury (DILI) is a complex and intractable disease because existing anti-oxidate therapies in clinic fail to modulate multiple pathological pathways concurrently. Here, we present a direction-aware framework that integrates disease...

Targeted protein degradation (TPD) has emerged as a transformative therapeutic strategy that offers unprecedented opportunities to eliminate traditionally "undruggable" proteins that have posed significant challenges in traditional drug development. ...