AIMC Journal:
Therapeutic delivery

Showing 1 to 7 of 7 articles

Nanotheragnosis: an emerging frontier review in personalized cancer medicine.

Therapeutic delivery
Cancer remains a major cause of global mortality, while late-stage diagnosis and therapeutic resistance highlight the need for individualized strategies. Nanotheranostics has emerged as a promising paradigm by integrating cancer diagnosis and treatme...

Smart nanocarriers against MDR-tuberculosis: stimuli-responsive strategies for granuloma penetration and next generation therapy.

Therapeutic delivery
Multidrug-resistant tuberculosis (MDR-TB) remains a global health concern due to long treatment durations, limited drug penetration into granulomatous lesions, systemic toxicity, and the persistence of dormant Mycobacterium tuberculosis. The granulom...

Nanostructured lipid carriers for intranasal cannabidiol delivery in Dravet and Lennox-Gastaut syndromes: bridging preclinical promise to clinical translation.

Therapeutic delivery
Dravet syndrome (DS) and Lennox-Gastaut syndrome (LGS) are severe developmental epileptic encephalopathies that appear in early childhood, are unresponsive to medications, and have a dismal neurodevelopmental prognosis. Most patients do not respond w...

Engineering strategies and translational progress in targeted nanoparticle drug delivery.

Therapeutic delivery
INTRODUCTION: Nanoparticle-based drug delivery has emerged as a transformative approach in modern therapeutics, offering improved targeting efficiency, enhanced pharmacokinetics, and reduced systemic toxicity compared to conventional drug delivery sy...

Naturally derived excipients in injectable nanomedicines: a systematic review of pharmacokinetic performance, regulatory readiness, and future quality by design perspectives.

Therapeutic delivery
INTRODUCTION: Naturally derived excipients such as lecithin, chitosan, and hyaluronic acid offer biocompatibility for injectable nanomedicines, although material variability may limit clinical translation. This systematic review evaluated pharmacokin...

Current modeling approaches for drug delivery to the central nervous system.

Therapeutic delivery
Central nervous system (CNS) disorders pose a major global health challenge, yet therapeutic development is impeded by the difficulty of delivering effective drug concentrations to the brain. Based on a literature search of PubMed, Scopus, and Google...

Nanogels for the targeted delivery of antibiotic and antimicrobial drugs.

Therapeutic delivery
Nanoparticle-based drug delivery systems represent a promising platform for advancing biomedical therapies. Among them, nanogels - three‑dimensional, crosslinked polymer networks - offer tunable structures that enable targeted and controlled drug del...