AIMC Journal:
Translational neurodegeneration

Showing 1 to 2 of 2 articles

Dysfunction of the neurovascular unit as a temporal driver in Alzheimer's pathogenesis.

Translational neurodegeneration
Extensive studies have shown that cerebrovascular dysfunction is a critical factor in the onset and progression of Alzheimer's disease (AD). Neurovascular unit (NVU) is impaired in AD brains, including damage of tight junction between endothelial cel...

Molecular mechanisms of exercise-induced improvements in Alzheimer's disease: a focus on lipid homeostasis.

Translational neurodegeneration
Alzheimer's disease (AD) is the most prevalent type of dementia, and its pathophysiological mechanisms involve multiple factors, including genomic factors, metabolomic factors, and environmental factors. Lipid dysregulation occurs both centrally and ...