The neuromodulator acetylcholine has been suggested to govern learning under uncertainty. Here, we investigated the role of muscarinic acetylcholine receptors in reward-guided learning and decision making under different degrees of uncertainty. We ad...
The automated classification of animals from photos is important in ecology and conservation biology for organizing and understanding the immense diversity of species, as well as facilitating effective conservation and management practices. It is equ...
Predicting transitions between health, disease, and death across biological systems remains an important challenge with significant implications for both ecological management and medical intervention. Although the principles underlying these transit...
Opioid addiction is characterized by escalating drug use, driven in part by negative reinforcement from withdrawal, but the neural processes linking withdrawal to increased drug-taking remain poorly understood. Here, we use multisite local field pote...
Humans can readily infer gender from diverse visual categories, including faces, bodies, and objects, yet it remains unclear whether the brain constructs a shared, category-general representation of gender. To fill the gap, we measured neural respons...
The sense of smell remains poorly understood, especially in contrast to visual and auditory coding. At the core of our sense of smell is the olfactory information flow, in which odorant molecules activate a subset of our olfactory receptors and combi...
Recent advancements in wearable sensors and machine learning show promise for estimating lower-body joint torques outside of laboratory settings. Inertial Measurement Units combined with Convolutional Neural Networks have proven effective for this ta...
Accurate prediction of drug synergy is paramount for developing effective combination therapies and advancing personalized medicine. Although methods based on graph neural networks (GNNs) have become a prevalent approach, they often treat molecules a...
Improving long-term memory in artificial neural networks remains an open challenge. To address this, we developed a novel brain-inspired framework for memory prioritization based on the principle of emotional valence. Our framework includes: (i) a va...
Artificial Intelligence (AI) has transformed biology by revealing patterns in large-scale datasets and predicting regulatory relationships. Yet even the most advanced models often fail to identify biologically meaningful mechanisms from statistical a...
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