AIMC Journal:
bioRxiv

Showing 2091 to 2100 of 4956 articles

Comparative study of two xanthan gum glycosyltransferases combining AI structure predictions and molecular modeling

bioRxiv
Xanthan gum is a widely used industrial polysaccharide employed as a thickening and stabilizing agent in food, pharmaceutical, and technological applications. Its biosynthesis involves membrane-associated glycosyltransferases that assemble the repeat...

invertmeeg: A Unified Python Library and Benchmark for 112 M/EEG Inverse Solvers

bioRxiv
Magnetoencephalography (MEG) and electroencephalography (EEG) source imaging requires solving an ill-posed inverse problem for which numerous algorithms have been proposed over the past decades. However, these methods are scattered across different p...

Uncovering genetic mechanisms underlying trait variation in switchgrass using explainable artificial intelligence

bioRxiv
Uncovering the genetic architecture of quantitative traits is challenging because polygenic control yields small individual gene effects and because gene-gene and genotype-by-environment interactions add further complexity. To understand the genetic ...

A general methodology for liver sinusoid fenestration analysis based on 3D electron microscopy data

bioRxiv
The liver has a complex architecture composed of millions of lobules. Within these lobules, hepatocytes, the main hepatic cells, are organized in rows separated by blood capillaries known as sinusoids. These capillaries are lined by liver sinusoidal ...

Photochromic reversion enables long-term tracking of single molecules in living plants.

bioRxiv
Single-molecule imaging enables the observation of individual molecules in living cells (D'Este et al., 2024; Kusumi et al., 2014; Lelek et al., 2021; Nguyen et al., 2023). In plants, however, the tracking of single molecules is typically limited to ...

From the fly connectome to exact ring attractor dynamics

bioRxiv
A cognitive compass enabling spatial navigation requires the neural representation of head direction (HD), yet the neural circuit architecture enabling this representation remains unclear. While various network models have been proposed to explain HD...

Sleep Disruption Improves Performance in Simple Olfactory and Visual Decision-Making Tasks

bioRxiv
Sleep disruption drastically impacts cognitive functions including decision-making and attention across many different species. In this study, we leveraged the small size and conserved vertebrate brain structure of larval zebrafish to investigate how...

A population code for semantics in human hippocampus

bioRxiv
As we listen to speech, our brains track the meanings of the words we hear. Recent successes of large language models suggest that distributed population geometry can capture rich semantic relationships between words. Motivated by this idea, we hypot...

REMAG: recovery of eukaryotic genomes from metagenomic data using contrastive learning

bioRxiv
Metagenome-assembled genomes (MAGs) are central to exploring microbial communities. Yet, despite the relevance of protists and fungi to diverse ecosystems, eukaryotic MAG recovery lags behind that of prokaryotes. A major bottleneck is that most state...

Perseus: Lineage-Aware Refinement of Kraken2 Taxonomic Classification for Long Read Metagenomes

bioRxiv
Motivation: Long-read metagenomic sequencing improves assembly contiguity and enables genome-resolved analysis of complex microbial communities, but accurate taxonomic classification of long reads and assembled contigs remains challenging. Highly sca...