Credit assignment in neural networks is usually formulated as the computation of an abstract error gradient. Whether such a gradient can take a physical, causal form in biophysically detailed multi-compartment neuron models, and enable online, superv...
The Alu transposable element is among the most abundant classes of mobile DNA in the human genome, and has been linked to gene regulation and chromatin organization. Yet how individual Alu insertions influence nearby chromatin interactions remains po...
Resting-state electroencephalography (EEG) can capture the slowing of neural oscillations associated with Alzheimers disease (AD), but many machine-learning studies remain difficult to inspect, reproduce, or test. This study developed an interpretabl...
Structure-based drug discovery is a widely used paradigm for the rational design of novel small molecule therapeutics. However, the benefits conferred by the use of structural information has seen limited adoption in machine learning, where ligand-on...
Conventional bibliometrics rely on lifetime citations, obscuring immediate shifts in cardiovascular research paradigms. To track emerging trends in atrial fibrillation management, we performed a comparative bibliometric analysis of the 50 highest-cit...
Prostate cancer, a leading cause of cancer-related deaths among men globally, necessitates the development of precise diagnostic and treatment strategies. Accurate segmentation of prostate cancer in medical imaging, particularly in MRI scans, is cruc...
Environmental DNA (eDNA) offers a non-invasive alternative to traditional, more destructive sampling methods for determining species occupancy at ecological sites of interest. Aquatic eDNA sampling entails filtering a known volume of water to capture...
Bone science literature spans biology, mechanics, materials science, and clinical medicine, and its volume makes reliable knowledge synthesis increasingly difficult. General-purpose large language models (LLMs) answer fluently but under-represent thi...
Neoantigen immunogenicity prediction is fundamental to personalized cancer vaccines, tumor-infiltrating lymphocyte (TIL) therapy, and TCR-T cell engineering. Existing computational predictors rely primarily on in-vitro correlates of peptide presentat...
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