Interictal epileptiform discharges (IEDs) are pathological hypersynchronous bursts of electrical brain activity that occur between seizures in patients with epilepsy. IEDs are caused by transient brain states that are difficult to predict, making the...
Recently developed deep learning-based tools can effectively generate structural models of complexes of proteins and non-proteinaceous compounds. While some of their predictive capabilities are truly exciting, others remain to be thoroughly tested. H...
Biomedical Knowledge Graphs (BKGs) offer integrative representations of complex biology, yet their utility is compromised by the limitations of current construction methods: manual curation offers high fidelity but is unscalable, whereas purely autom...
Sodium azide mutagenesis offers a powerful approach to generate genetic diversity for rice improvement, yet comprehensive characterization of mutant populations using integrated modern breeding tools remains limited. M3 mutants of BRRI dhan28-induced...
Introduction: Supervised statistical learning for cell-level segmentation and morphometry in optical microscopy is limited less by algorithmic capacity than by the scarcity of reliable, expert-validated ground truth. In comparative neuroscience and q...
Advances in single-cell multimodal profiling have enabled a more systematic analysis of cellular biology, yet the rapid accumulation of large-scale, heterogeneous datasets poses substantial challenges for integrative analysis. Recently, Transformer-b...
Understanding how perturbations influence gene function in a tissue-specific manner is key to uncovering novel drug targets. However, current computational approaches emphasize global network or sequence-derived features over context-driven dependenc...
Computed Tomography (CT) is one of the largest contributors to radiation exposure from medical imaging, which can induce DNA damage and increase cancer risk. Reducing CT radiation dose to improve patient safety inherently increases image noise and ar...
Standard approaches to bacterial phenotyping often treat the entire genome as the fundamental unit of information, resulting in high-dimensional inputs that may contain significant redundancy. Consequently, current bacterial phenotyping techniques ty...
When learning to find the most beneficial course of action, the prefrontal cortex guides decisions by comparing estimates of the relative value of the options available. Basic neuroscience studies in animals support the view that the thalamus can reg...
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