AIMC Journal:
bioRxiv

Showing 2431 to 2440 of 4979 articles

X-SPATIO: An Explanatory Deep Learning Pipeline for the Prediction and Visualization of Spatially Resolved Biomarker Expression in Triple-Negative Breast Cancer

bioRxiv Feb 11, 2026
Histopathologic evaluation remains central to cancer diagnosis and treatment planning, yet the molecular programs underlying distinct tissue morphologies are not routinely accessible in clinical workflows. Spatial transcriptomic/proteomic platforms p...
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Multiplexed high-content imaging uncovers morphological diversity of lymphocyte activation and dysfunction

bioRxiv Feb 11, 2026
Single-cell transcriptomic and proteomic technologies enable molecular profiling of immune cells at scale but provide limited access to cellular phenotypes shaped by spatial organisation, organelle architecture and cytoskeletal remodelling. Here we p...
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GeneReL: A Large Language Model-Powered Platform for Gene Regulatory Relationship Extraction with Community Curation

bioRxiv Feb 11, 2026
Motivation: Gene regulatory networks provide fundamental insights into plant biology, yet extracting structured interaction data from scientific literature remains a significant bottleneck. Traditional manual curation cannot scale to meet the demands...
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From Lipid Dynamics to Precision Predictions: A New Approach Method for Precision Modeling of Phosphoinositide Signaling

bioRxiv Feb 10, 2026
Precision medicine requires models that can translate rich molecular measurements into individualized predictions of biological response. Phosphoinositide signaling disorders present an acute challenge, where nonlinear dynamics vary across cell types...
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Self-supervised learning yields representational signatures of category-selective cortex

bioRxiv Feb 10, 2026
The ventral visual stream contains category-selective regions with distinct feature tuning, most prominently the fusiform face area (FFA) and parahippocampal place area (PPA). Why do these brain regions exhibit distinct tuning properties? Here, we te...
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Automated Monitoring of Insects system: Building a non-lethal and scalable solution for monitoring of nocturnal insects

bioRxiv Feb 10, 2026
There is growing evidence that human-induced climate change and habitat loss are having negative impacts on insect populations. New technologies have a vital role in improving and expanding global biodiversity monitoring capacity to understand where ...
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Virtual Immersion in Biomedical Engineering (VIBE): Exposing undergraduates to culturally sensitive engineering design and professional experiences at scale

bioRxiv Feb 10, 2026
Challenge: Undergraduate engineering students often face two major barriers: limited access to culturally sensitive global experiences and difficulty securing design internship opportunities. Traditional study abroad and internship programs can be in...
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Token Alignment for Verifying LLM-Extracted Text

bioRxiv Feb 10, 2026
Large language models excel at text extraction, but they sometimes hallucinate. A simple way to avoid hallucinations is to remove any extracted text that does not appear in the original source. This is easy when the extracted text is contiguous (find...
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When attention falters: brain, breathing, and behavioral signals of lapses in interoceptive attention

bioRxiv Feb 10, 2026
Mind-body practices like meditation and yoga, which are widely used to support mental health, involve paying attention to internal bodily sensations like the breath. During these practices, individuals often report "interoceptive lapses," moments whe...
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Integration and harmonization of cell shape images for generative modeling

bioRxiv Feb 10, 2026
As cell imaging grows in scale, precision, and complexity, data integration and harmonization become increasingly important for studying cell material interactions. Quantitative understanding of how cells respond to mechanical cues, such as substrate...
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