AIMC Journal:
bioRxiv

Showing 391 to 400 of 4935 articles

Dissecting Immune-Epithelial Interactions in Airway Infection at Single-Cell Resolution Using a Compartmentalised Microfluidic Device

bioRxiv Aug 25, 2026
Immune-epithelial interactions govern the initiation and progression of airway diseases, yet their heterogeneity is difficult to capture using existing in vitro models. Although conventional Transwell and lung-on-chip systems reproduce airway compart...
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A multimodal perturbation atlas defines the phenotypic resolution of cellular morphology.

bioRxiv Aug 25, 2026
Modeling cellular behavior requires measurements that capture how cells evolve across time, environments, and interventions. Microscopy is uniquely suited to this goal: it is non-destructive and can be applied to living cells in their native context....
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PINN-ing the Balloon: A Physically Informed Neural Network Modelling the Nonlinear Haemodynamic Response Function in MRI

bioRxiv Aug 25, 2026
Accurate characterisation of the haemodynamic response function (HRF) is central to interpreting blood-oxygen-level-dependent (BOLD) signals in functional magnetic resonance imaging, yet standard estimation approaches remain centred around phenomenol...
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Artificial Intelligence Model: Optimizing Cancer Risk Level Predictions Using Machine learning and deep learning approaches

bioRxiv Aug 25, 2026
This study emphasizes the potential of computational techniques in cancer risk assessment, lighting opportunities for specific and data-driven healthcare solutions. This study examines the use of artificial intelligence (AI), machine learning (ML), a...
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Transcriptomic Changes and Biomarkers in Barrett's Metaplasia, Dysplasia and Cancer

bioRxiv Aug 25, 2026
Esophageal adenocarcinoma (EAC) has a poor five-year survival rate and one of the fastest-rising incidences of any cancer. The presence of dysplasia in Barrett's esophagus (BE) is the main risk factor for EAC development and guides clinical managemen...
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Bridging Morphology and Genomics: A rapid image-based assessment of genomic admixture in the endangered gayal (Bos frontalis)

bioRxiv Aug 25, 2026
Abstract The gayal (Bos frontalis) is an endangered semi-domesticated bovine species renowned for its high-quality beef. However, its semi-feral lifestyle, ongoing habitat fragmentation, and extensive genetic introgression from sympatric local cattle...
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MPGEM: A harmonized and transcriptome-complete resource for large-scale reuse of legacy human microarray data

bioRxiv Aug 25, 2026
Abstract Background: Legacy microarray datasets provide an extensive record of human transcriptomic biology, but their reuse is constrained by differences in platform design, preprocessing, measurement scale, and gene coverage. Platforms measuring on...
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CCIDeconv: Hierarchical model for deconvolution of subcellular cell-cell interactions in single-cell data

bioRxiv Aug 25, 2026
Cell-cell interaction (CCI) underlies several fundamental biological processes, including development, homeostasis and disease progression. Subcellular spatial transcriptomics (sST) provides an opportunity to examine whether CCI-associated signals sh...
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Spoken Recall Reveals Lexical and Mnemonic Function Differences in Temporal Lobe Epilepsy Patients

bioRxiv Aug 25, 2026
Background and Objectives: Word-finding difficulty is common in healthy aging and in neurologic disorders, including temporal lobe epilepsy (TLE) and early Alzheimer disease. Standard language measures have limited sensitivity for detecting subtle or...
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Detecting CYP2C19 deletions from genotyping array signals using neural networks

bioRxiv Aug 25, 2026
Since copy number variations (CNVs) in pharmacogenes can cause significant alterations in drug metabolism, their reliable detection is of high importance both for large-scale studies and personalized medicine. Whole-genome sequencing, and specificall...
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