Solitary bee species that use artificial trap nests are important for agricultural crop production and as indicators of habitat quality. Quantifying cavity-nesting solitary bee foraging and nesting behavior is essential for real-time analysis of popu...
Asian rice is one of the best documented crops in terms of genetic diversity. The domestication process, that probably started 9000 years ago in China, remains difficult to infer since the main vertical signal is blurred by horizontal signals related...
Oxytocin-mediated milk ejection (ME) is pivotal to effective breastfeeding and productive health, yet behaviorally decoding and revealing neural mechanisms of ME remains challenging. Here, we combined in vivo calcium imaging and intramammary pressure...
Body size is an important trait that reflects animal development and physiology. In nematodes, precise measurement is valuable for linking variation in body dimensions to biological questions such as developmental timing, genetic regulation, and drug...
Reverse vaccinology has enabled sequence-based antigen discovery, but it overlooks the rich semantic knowledge embedded in the biomedical literature. Here we establish Semantic Vaccinology (SemVac), a paradigm that leverages large language models (LL...
Importance. Callous Unemotional (CU) traits are associated with significant clinical and neurophysiological heterogeneity that may affect treatment effectiveness. Objective. To uncover neuroanatomical subtypes of CU traits using weakly-supervised mac...
The rapid expansion of chimeric antigen receptor (CAR) T cell studies has produced a fragmented evidence landscape linking publications, repository accessions, patient metadata and mechanistic observations. Here we present BioPathfinder, a multi-agen...
Antibodies raised against human targets often fail to recognize their animal orthologs, limiting preclinical evaluation in relevant models. We developed a Deep Mutational Scanning (DMS)-coupled deep learning strategy to engineer potent cross-reactive...
Surprisal and contextual embeddings are both derived from large language models and are widely used to predict neural responses during language comprehension, but it is unclear whether surprisal adds information beyond embeddings. We test this direct...
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