Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 14,461 to 14,470 of 211,815 articles

Equilibrium Propagation with Predictive Learning in Leaky Integrate-and-Fire Spiking Neural Networks

bioRxiv May 21, 2026
Equilibrium propagation (EP) is a biologically plausible alternative to backpropagation that has demonstrated competitive performance across a range of machine learning tasks. Recent work has extended EP to spiking neural networks (SNNs), leveraging ... read more 
neuroscience

Antimicrobial peptide databases and prediction tools: Toward a standard evaluation framework

bioRxiv May 21, 2026
Antimicrobial resistance (AMR) has a profound impact on animal and human health and is associated with substantial morbidity, mortality and public health costs. There is a clear need to develop novel, effective antibiotic agents, which can overcome t... read more 
bioinformatics

DigitAb: Domain-Adaptive Cell Type Prediction Method from Light Microscopy Images

bioRxiv May 21, 2026
Light microscopy imaging with histological stains is central to disease diagnosis and research. It is enhanced with immunostaining to reveal cellular composition and complexity linked to clinical utility and biological mechanisms. Emerging multiplex ... read more 
pathology

A single-nucleotide change in the Kozak sequence enhances protein expression

bioRxiv May 21, 2026
In vitro-transcribed messenger RNA (IVT mRNA) has emerged as a versatile protein expression platform with broad clinical potential. Current optimization strategies for IVT mRNA focus on untranslated regions (UTRs), mRNA stability, and codon usage, of... read more 
bioengineering

RANKOR: Direct Drug Prioritization from Bulk and Single-Cell Transcriptomic Signatures

bioRxiv May 21, 2026
Background Prioritizing therapeutics from transcriptomic data remains a key challenge in precision medicine. Signature reversal approaches, most commonly implemented through Gene Set Enrichment Analysis (GSEA), have been widely used to match disease ... read more 
bioinformatics

Membrane proteomics of the Drosophila circadian neural network

bioRxiv May 21, 2026
Circadian behaviors are controlled by dedicated brain pacemaker neurons, whose activity oscillate during the day and the night. The Drosophila brain contains ca. 240 such neurons. Their molecular clock is synchronized, but the phase of their rhythmic... read more 
neuroscience

Synaptic pruning, myelination and the emergence of psychiatric disorders in late adolescence

bioRxiv May 21, 2026
Adolescence is an important developmental period during which there are diverse changes in the brain and behavior. Goal-directed behaviors and the component processes underlying those behaviors improve during adolescence, including working memory, re... read more 
neuroscience

Rhythmic temporal structure organizes recurrent dynamics to support sequential working memory

bioRxiv May 21, 2026
Rhythmic temporal structure improves working memory, but how this benefit emerges from recurrent dynamics remains unclear. Here, we trained excitatory-inhibitory recurrent neural networks with short-term synaptic plasticity to perform a sequential de... read more 
neuroscience

AI-assisted improvement of Aspergillus oryzae β-galactosidase using an Ensemble of Protein Language Models

bioRxiv May 21, 2026
{beta}-galactosidases (BGs) are essential enzymes widely used in the food industry, particularly in the production of lactose-free products. Among them, the BG from Aspergillus oryzae is of industrial relevance due to its activity at acidic pH and mo... read more 
synthetic biology

A Bioprinted Head and Neck Cancer Organoid-Based Platform for Evaluating Multimodal Therapies

bioRxiv May 21, 2026
Treatment of advanced head and neck squamous cell carcinoma (HNSCC) often involves radiotherapy combined with chemotherapy, targeted therapy, or immunotherapy. However, due to its anatomical and molecular heterogeneity, identifying the most effective... read more 
cancer biology
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