Purpose: To demonstrate the feasibility of prostate MRI at low-field and provide an optimised low-field prostate MRI protocol. Methods: We acquired bi-parametric prostate MRI in 15 healthy male volunteers (mean age 62 years, 95% CI 57-67.5), includin... read more
Timely identification of hospital inpatients at risk of deterioration facilitates interventions to support their recovery. Many hospitals implement early warning scores to detect abnormal patient vital signs, such as the National Early Warning Score ... read more
Background and objective: High-risk non-muscle-invasive bladder cancer (HR-NMIBC) is treated with transurethral resection and intravesical BCG instillations, yet approximately 50% recur and 20% progress to invasive disease. Although molecular subtypi... read more
Individuals adapt their behavior in response to infectious disease epidemics. Understanding the determinants of behavior, particularly the impact of infections themselves, can help model the feedback loop between disease and behavior in epidemic mode... read more
Electroencephalography (EEG) interpretation in clinical practice relies on the analysis of energy distribution across standard frequency bands. The Weed Plot framework encodes band wise spectral energy, computed using Fourier based methods, into a sy... read more
Background. Dengue has been a major health threat globally in recent years. In particular, dengue incidences continue to increase annually and the epidemic area has expanded primarily due to global warming. Therefore, effective case detection and sur... read more
Importance: Implantable sub-scalp EEG systems with a small number of channels have emerged as promising solutions for long-term seizure monitoring in patients with epilepsy. How seizure detection performance varies by montage configuration is unknown... read more
Background: Integrating multimodal data into medical artificial intelligence (AI) tools and evaluating whether they outperform human experts remains a critical challenge. Epilepsy surgery offers a unique paradigm for this evaluation, as it provides a... read more
Virtual screening has become an indispensable tool in modern structure-based drug discovery, enabling the identification of candidate molecules by computationally evaluating their potential to bind target proteins. The accuracy of such screenings cri... read more
Mechanistic modeling has long been used as a tool to describe the dynamics of biological systems, especially cancer in response to treatment. Their key advantage lies in interpretability of relationships between input parameters and outcomes of inter... read more
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