Although the molecular regulation of hematopoiesis is well characterized, the spatial organization of hematopoietic cells within bone marrow (BM) remains unclear. Advances in microscopy have produced increasingly detailed images of murine BM, yet acc... read more
Organoids have rapidly matured into powerful model systems. The field is pushing organoids toward architectural sophistication and functional fidelity, with longitudinal experiments producing ever-larger and more complex datasets. As a result, comput... read more
RATIONALE AND OBJECTIVES: This study aimed to develop and validate a deep learning-based brain metastasis detection model (BMDM) in magnetic resonance images for diagnosing brain metastases (BMs). MATERIALS AND METHODS: We retrospectively collected d... read more
OBJECTIVES: The quantitative analysis of 16-segment left ventricular wall thickness can provide insights into the pathological progression of left ventricular hypertrophy, influencing diagnosis and treatment. However, its applications were time-consu... read more
Over the past 2 decades, risk stratification in non-muscle-invasive bladder cancer (NMIBC) has evolved considerably, progressing from simple clinico-pathologic scoring systems to sophisticated, molecular, and artificial intelligence (AI)-driven frame... read more
INTRODUCTION: Peripherally inserted central catheters (PICCs) are increasingly used in France for prolonged intravenous therapies such as chemotherapy, parenteral nutrition, or antibiotics. They are easier to place than traditional central venous cat... read more
Best practice & research. Clinical rheumatology
Mar 13, 2026
Psoriatic arthritis is a heterogeneous disease where delayed diagnosis and variable treatment responses remain significant challenges. This review addresses how interconnected metabolic, immunological, and genetic pathways provide opportunities for p... read more
Recent advances in drug delivery and formulation
Mar 13, 2026
Artificial nanomaterials known as nanozymes, which possess inherent enzyme-mimetic characteristics, have transformed environmental research, biomedicine, and catalysis. Compared with natural enzymes, nanozymes are advantageous due to their high stabi... read more
INTRODUCTION: The permeability of the blood-brain barrier (BBB) is an important property for potential drugs. Various in vitro and in vivo methods have been established to measure bloodbrain transport. Nevertheless, empirical assessment of the blood-... read more
INTRODUCTION: Cancer is a major global health concern, causing millions of deaths each year due to the uncontrolled growth and spread of abnormal cells. Despite advances in diagnosis and treatment, its complexity and therapy resistance keep it a lead... read more
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