Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 42,561 to 42,570 of 223,853 articles

mRNA-Protein Coordination is Contextualized by Metastatic Biological Phenotypes

bioRxiv Mar 11, 2026
A central goal of conducting omics measurements is to understand how molecular features inform higher-order cell- and tissue-level phenotypes. In particular, multi-omics offers insights into how information encoded by the genome is coordinated throug... read more 
systems biology

Automated extraction and optimization of protein purification protocols using multi-agent large language models

bioRxiv Mar 11, 2026
Recent advances in Large Language Models (LLMs) present new opportunities for automating critical bottlenecks in scientific workflows such as literature reviews or protocol design. One such bottleneck is the purification of recombinant proteins, a vi... read more 
bioinformatics

HAETAE: A highly accurate and efficient epigenome transformer for tissue-specific histone modification prediction

bioRxiv Mar 11, 2026
While genomic models trained on four bases often fail to capture cell-type specificity, we introduce HAETAE, which integrates 5-methylcytosine from long-read sequencing into a 5-base framework. By explicitly modeling epigenetic context, HAETAE achiev... read more 
bioinformatics

EmbryoTempoFormer: clip-based developmental tempo inference from zebrafish brightfield time-lapse microscopy

bioRxiv Mar 11, 2026
Quantitative changes in zebrafish embryonic developmental tempo are key phenotypes in drug screening, genetic perturbation, and environmental stress studies. However, manual staging is labor-intensive and subjective, and nominal hours post fertilizat... read more 
developmental biology

Distinct cellular DNA methylation mechanisms underlie common and rare genetic risk for brain disorders

bioRxiv Mar 11, 2026
Noncoding genetic variation contributes to brain disorder risk, but the mechanisms through which it acts in specific brain cell types remain unclear. DNA methylation (DNAm), a highly cell type-specific regulatory layer in the brain, may mediate nonco... read more 
genetics

Cell-type-specific sustained value representations in the claustrum

bioRxiv Mar 11, 2026
Flexible decision-making relies on interactions between frontal cortex and subcortical structures. The claustrum, a subcortical nucleus highly interconnected with frontal cortex, influences cortical activity and has been implicated in cognitive funct... read more 
neuroscience

Continuous Estimation of Achilles Tendon Loading in Rupture Patients Using a Single Boot-Mounted Accelerometer

medRxiv Mar 11, 2026
Objective: Achilles tendon ruptures lead to long-term structural and functional deficits. Prior research that sought to identify optimal rehabilitation techniques was fundamentally limited by the inability to continuously monitor Achilles tendon load... read more 
orthopedics

Regression vs. Medical LLMs: A Comprehensive Study for CVD and Mortality Risk Prediction

medRxiv Mar 11, 2026
Cardiovascular diseases (CVDs) remain the foremost cause of global morbidity and mortality, driving an urgent need for robust predictive tools that enable early detection and preventive intervention. Traditional regression based models such as linear... read more 
health informatics

The Risk Factors, Detection and Classification of Esophageal Cancer Using Ensemble Machine Learning Models

medRxiv Mar 11, 2026
Esophageal cancer (EC) remains one of the most lethal malignancies worldwide, with poor survival outcomes largely attributable to late-stage diagnosis and limited treatment effectiveness. Early detection and accurate risk stratification are therefore... read more 
health informatics

Integrating AI-powered automated neurovascular bundle segmentation and radiomics for prostate cancer staging

medRxiv Mar 11, 2026
Background: Assessment of the prostatic neurovascular bundles on MRI is clinically relevant for staging and treatment planning but remains technically challenging and underexplored in automated imaging pipelines. Purpose: To develop and evaluate an a... read more 
oncology
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