AI Medical Compendium

Quantum-inspired deep learning model for organic municipal solid waste classification toward a circular bioeconomy.

Journal of environmental management Mar 11, 2026

Organic waste constitutes a major portion of total municipal solid waste and plays a critical role in sustainable waste management. Proper segregation of organic waste at the source is necessary for improving the waste processing efficiency and facil... read more

Response of microbial nitrogen removal to sinuosity in river bends: mechanisms and development of physics-informed neural networks model.

Journal of environmental management Mar 11, 2026

Understanding the underlying mechanism of biogeochemical processes in river bends is important for decisions on sinuosity in river construction to improve the self-purification capability. Complex flow deeply modified by sinuosity in river bends crea... read more

G-quadruplexes and i-motifs: Emerging regulatory elements in plant genomes.

Current opinion in plant biology Mar 11, 2026

G-quadruplexes (G4s) and i-motifs (iMs) are emerging as key cis-regulatory elements in plant genomes, functioning at both DNA and RNA levels. This review summarizes recent progress in their identification and prediction, including sequencing-based de... read more

Design of an optimal planning framework for cryosurgical treatment of brain tumor using CNN segmentation of MRI images.

Cryobiology Mar 11, 2026

This study presents an integrated methodology for pre-operative cryosurgical planning of irregularly shaped brain tumors using two-dimensional MRI data. Tumor regions were first segmented from MRI slices using a 2D U-Net architecture trained on annot... read more

Untangling biological complexity: A deep learning approach to separating multiple signals in single-cell data.

Cell genomics Mar 11, 2026

Single-cell RNA sequencing (scRNA-seq) provides an instantaneous snapshot of the transcriptional state of a cell, which results from the simultaneous activity of many cellular processes. In this issue of Cell Genomics, Chen et al.1 describe the devel... read more

De novo design of Ras isoform selective binders.

Cell chemical biology Mar 11, 2026

The four major isoforms encoded by RAS proto-oncogenes are differentially associated with cancer, but there are few isoform-specific binding reagents becasue the sequence differences are confined to their disordered C termini. To overcome this limita... read more

Heart rate and sleep history encode ultradian REM sleep timing.

Current biology : CB Mar 11, 2026

During sleep, the brain alternates between rapid eye movement (REM) and non-REM (NREM) sleep, with recurring REM sleep episodes forming the ultradian sleep cycle, a hallmark of mammalian sleep. However, the mechanisms regulating the ultradian timing ... read more

Cell-type-specific transposon demethylation and TAD remodeling in aging mouse brain.

Cell Mar 11, 2026

Aging is a major risk factor for neurodegenerative diseases, yet the underlying epigenetic mechanisms remain unclear. Here, we generated a comprehensive single-nucleus cell atlas of brain aging across multiple brain regions, comprising 132,551 single... read more

Automatic deep learning-based segmentation of cornea and lens in 2D OCT images of rabbit eyes.

Experimental eye research Mar 11, 2026

Anterior-segment optical coherence tomography (AS-OCT) supports cataract surgery planning by revealing corneal and crystalline lens geometry, but clinical workflows require fast, user-independent delineation of key interfaces in noisy scans. We addre... read more

Beyond spectroscopy: Machine vision as the future of non-destructive testing in 3D-printed pharmaceuticals.

International journal of pharmaceutics Mar 11, 2026

3D Printing (3DP) has revolutionized personalized medicine by enabling the production of patient-specific dosage forms and adaptable drug delivery systems. However, despite these advances, 3DP presents significant challenges in quality control (QC), ... read more

Artificial Intelligence Medical Compendium