Designing peptide binders is a widely used strategy for developing potential therapeutic agents. Fibroblast Growth Factor 7 (FGF7) plays a critical role in cell proliferation and tissue repair, and its dysregulation is associated with various disease... read more
Computer methods and programs in biomedicine
Jan 3, 2026
BACKGROUND AND OBJECTIVE: This study introduces the liver cancer segmentator (LCS), a deep learning model designed for automatic and robust segmentation of liver parenchyma and tumors in abdominal contrast-enhanced computed tomography images from pat... read more
Comparative biochemistry and physiology. Part D, Genomics & proteomics
Jan 3, 2026
Salinity fluctuation is a major environmental driver influencing fish physiology and aquaculture performance. Metabolomics offers a systems perspective on the small molecule networks underlying osmoregulation. This review synthesizes studies across f... read more
Accurate and efficient non-destructive evaluation (NDE) techniques are essential for ensuring the structural integrity of metallic components, where surface defects, as one of the most common types, can severely compromise fatigue life and mechanical... read more
This review examines the emerging integration of nanosensor networks with modern information and communication technologies to address critical needs in healthcare, environmental monitoring, and smart infrastructure. It evaluates how machine learning... read more
Accurate modulation classification is a core challenge in cognitive radio, adaptive communications, spectrum analysis and related domains especially under dynamic channels without transmitter knowledge. To address this need, the article presents a la... read more
Inline, non - destructive diagnostics are essential for controlling electrode quality in roll - to - roll battery manufacturing to minimise the cost and wasting valuable minerals. Ultrasonic pulse - echo is sensitive to thickness, density, and porosi... read more
European journal of medicinal chemistry
Jan 3, 2026
The quinazoline-based Aurora kinase inhibitor 9h, previously developed by our group, exhibited potent efficacy both in vitro and in vivo. However, its further development was hindered by a short half-life and insufficient metabolic stability. To addr... read more
International journal of medical informatics
Jan 3, 2026
BACKGROUNDS: Liver transplantation (LT) is a life-saving procedure for patients with end-stage liver disease, yet post-operative complications, particularly the need for respiratory support, remain a significant challenge. We aimed to develop and val... read more
BACKGROUND: Accurate preoperative evaluation of rectal cancer is essential for staging and treatment planning. Low-energy virtual monoenergetic imaging (VMI) enhances iodine contrast in dual-energy computed tomography (DECT) but increases image noise... read more
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